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PHARMACOLOGICAL EVIDENCE FOR A ROLE OF THE TRANSIENT RECEPTOR POTENTIAL CANONICAL 3 (TRPC3) CHANNEL IN ENDOPLASMIC RETICULUM STRESS-INDUCED APOPTOSIS OF HUMAN CORONARY ARTERY ENDOTHELIAL CELLS

Unresolved endoplasmic reticulum (ER) stress, with the subsequent persistent activation of the unfolded protein response (UPR) is a well-recognized mechanism of endothelial cell apoptosis with a major impact on the integrity of the endothelium during the course of cardiovascular diseases. As in othe...

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Detalhes bibliográficos
Publicado no:Vascul Pharmacol
Main Authors: Ampem, Prince T., Smedlund, Kathryn, Vazquez, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706806/
https://ncbi.nlm.nih.gov/pubmed/26215710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2015.07.011
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