Nitrogen mustard-induced corneal injury involves DNA damage and pathways related to inflammation, epithelial-stromal separation and neovascularization

PURPOSE: To evaluate the toxic effects and associated mechanisms in corneal tissue exposed to vesicating agent, nitrogen mustard (NM), a bi-functional alkylating analog of chemical warfare agent sulfur mustard (SM). METHODS: Toxic effects and associated mechanisms were examined in maximal affected c...

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Publicado no:Cornea
Main Authors: Goswami, Dinesh G, Tewari-Singh, Neera, Dhar, Deepanshi, Kumar, Dileep, Agarwal, Chapla, Ammar, David A, Kant, Rama, Enzenauer, Robert W, Petrash, J Mark, Agarwal, Rajesh
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706783/
https://ncbi.nlm.nih.gov/pubmed/26555588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ICO.0000000000000685
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