Topical nitrogen mustard exposure causes systemic toxic effects in mice

Vesicating agents sulfur mustard (SM) and nitrogen mustard (NM) are reported to be easily absorbed by skin upon exposure causing severe cutaneous injury and blistering. Our studies show that topical exposure of NM (3.2 mg) onto SKH-1 hairless mouse skin, not only caused skin injury, but also led to...

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Detalhes bibliográficos
Publicado no:Exp Toxicol Pathol
Main Authors: Goswami, Dinesh G., Kumar, Dileep, Tewari-Singh, Neera, Orlicky, David J., Jain, Anil K., Kant, Rama, Rancourt, Raymond C., Dhar, Deepanshi, Inturi, Swetha, Agarwal, Chapla, White, Carl W., Agarwal, Rajesh
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308427/
https://ncbi.nlm.nih.gov/pubmed/25481215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.etp.2014.11.006
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