Ablating hedgehog signaling in tenocytes during development impairs biomechanics and matrix organization of the adult murine patellar tendon enthesis

Restoring the native structure of the tendon enthesis, where collagen fibers of the midsubstance are integrated within a fibrocartilaginous structure, is problematic following injury. As current surgical methods fail to restore this region adequately, engineers, biologists, and clinicians are workin...

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Pubblicato in:J Orthop Res
Autori principali: Breidenbach, Andrew P., Aschbacher‐Smith, Lindsey, Lu, Yinhui, Dyment, Nathaniel A., Liu, Chia‐Feng, Liu, Han, Wylie, Chris, Rao, Marepalli, Shearn, Jason T., Rowe, David W., Kadler, Karl E., Jiang, Rulang, Butler, David L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706742/
https://ncbi.nlm.nih.gov/pubmed/25807894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22899
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