Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells

BACKGROUND: Histone deacetylase (HDAC) inhibitors are widely used in clinical investigation as novel drug targets. For example, panobinostat and vorinostat have been used to treat patients with melanoma. However, HDAC inhibitors are small-molecule compounds without a specific target, and their mecha...

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Bibliografiska uppgifter
I publikationen:J Transl Med
Huvudupphovsmän: Liu, Jiaqi, Gu, Jianying, Feng, Zihao, Yang, Yanhong, Zhu, Ningwen, Lu, Weiyue, Qi, Fazhi
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706654/
https://ncbi.nlm.nih.gov/pubmed/26747087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0753-0
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