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Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells

BACKGROUND: Histone deacetylase (HDAC) inhibitors are widely used in clinical investigation as novel drug targets. For example, panobinostat and vorinostat have been used to treat patients with melanoma. However, HDAC inhibitors are small-molecule compounds without a specific target, and their mecha...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Liu, Jiaqi, Gu, Jianying, Feng, Zihao, Yang, Yanhong, Zhu, Ningwen, Lu, Weiyue, Qi, Fazhi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706654/
https://ncbi.nlm.nih.gov/pubmed/26747087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0753-0
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