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Mycoplasma penetrans Is Capable of Activating Vγ9/Vδ2 T Cells While Other Human Pathogenic Mycoplasmas Fail To Do So

While most mycoplasma species appear to have evolutionarily lost the ability to synthesize isoprenoid precursors, Mycoplasma penetrans has retained the nonmevalonate pathway that proceeds via the immunogenic intermediate (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMB-PP). Consequently, this pa...

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Autori principali: Eberl, Matthias, Hintz, Martin, Jamba, Zandraa, Beck, Ewald, Jomaa, Hassan, Christiansen, Gunna
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC470652/
https://ncbi.nlm.nih.gov/pubmed/15271953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.8.4881-4883.2004
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