Mycoplasma penetrans Is Capable of Activating Vγ9/Vδ2 T Cells While Other Human Pathogenic Mycoplasmas Fail To Do So

While most mycoplasma species appear to have evolutionarily lost the ability to synthesize isoprenoid precursors, Mycoplasma penetrans has retained the nonmevalonate pathway that proceeds via the immunogenic intermediate (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMB-PP). Consequently, this pa...

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Detalhes bibliográficos
Main Authors: Eberl, Matthias, Hintz, Martin, Jamba, Zandraa, Beck, Ewald, Jomaa, Hassan, Christiansen, Gunna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC470652/
https://ncbi.nlm.nih.gov/pubmed/15271953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.8.4881-4883.2004
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