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Salmon-derived thrombin inhibits development of chronic pain through an endothelial barrier protective mechanism dependent on APC

Many neurological disorders are initiated by blood-brain barrier breakdown, which potentiates spinal neuroinflammation and neurodegeneration. Peripheral neuropathic injuries are known to disrupt the blood-spinal cord barrier (BSCB) and to potentiate inflammation. But, it is not known whether BSCB br...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Smith, Jenell R, Galie, Peter A, Slochower, David R, Weisshaar, Christine L., Janmey, Paul A, Winkelstein, Beth A
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706481/
https://ncbi.nlm.nih.gov/pubmed/26708087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.11.062
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