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How dynein moves along microtubules

Cytoplasmic dynein, a member of the AAA family of ATPases, drives the processive movement of numerous intracellular cargos towards the minus end of microtubules. Here, we summarize the structural and motile properties of dynein and highlight features that distinguish this motor from kinesin-1 and my...

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Bibliographic Details
Published in:Trends Biochem Sci
Main Authors: Bhabha, Gira, Johnson, Graham T., Schroeder, Courtney M., Vale, Ronald D.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706479/
https://ncbi.nlm.nih.gov/pubmed/26678005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2015.11.004
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