TLR4 regulates pulmonary vascular homeostasis and remodeling via redox signaling

Pulmonary arterial hypertension (PAH) contributes to morbidity and mortality of patients with lung and heart diseases. We demonstrated that hypoxia induced PAH and increased pulmonary arterial wall thickness in wild-type mice. Mice deficient in toll-like receptor 4 (TLR4−/−) spontaneously developed...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Front Biosci (Landmark Ed)
Asıl Yazarlar: Ma, Liping, Ambalavanan, Namasivayam, Liu, Hui, Sun, Yong, Jhala, Nirag, Bradley, Wayne E., Dell’Italia, Louis J., Michalek, Sue, Wu, Hui, Steele, Chad, Benza, Raymond L, Chen, Yabing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706231/
https://ncbi.nlm.nih.gov/pubmed/26709781
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