TLR4 regulates pulmonary vascular homeostasis and remodeling via redox signaling

Pulmonary arterial hypertension (PAH) contributes to morbidity and mortality of patients with lung and heart diseases. We demonstrated that hypoxia induced PAH and increased pulmonary arterial wall thickness in wild-type mice. Mice deficient in toll-like receptor 4 (TLR4−/−) spontaneously developed...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Biosci (Landmark Ed)
Päätekijät: Ma, Liping, Ambalavanan, Namasivayam, Liu, Hui, Sun, Yong, Jhala, Nirag, Bradley, Wayne E., Dell’Italia, Louis J., Michalek, Sue, Wu, Hui, Steele, Chad, Benza, Raymond L, Chen, Yabing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706231/
https://ncbi.nlm.nih.gov/pubmed/26709781
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