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Attenuation of the Bacterial Load in Blood by Pretreatment with Granulocyte-Colony-Stimulating Factor Protects Rats from Fatal Outcome and Brain Damage during Streptococcus pneumoniae Meningitis

A model of pneumococcal meningitis in young adult rats receiving antibiotics once the infection was established was developed. The intent was to mimic clinical and histopathological features of pneumococcal meningitis in humans. The primary aim of the present study was to evaluate whether medical bo...

詳細記述

保存先:
書誌詳細
出版年:Infect Immun
主要な著者: Brandt, Christian T., Lundgren, Jens D., Lund, Søren Peter, Frimodt-Møller, Niels, Christensen, Thomas, Benfield, Thomas, Espersen, Frank, Hougaard, David M., Østergaard, Christian
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC470620/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15271925/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.8.4647-4653.2004
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