Lack of association between TDP-43 pathology and tau mis-splicing in Alzheimer's disease

A proportion of Alzheimer's disease cases displays inclusions of the RNA-binding protein, TDP-43. Considering the pathogenic role of tau mis-splicing, we compared tau isoform expression between Alzheimer's disease cases with or without TDP-43 inclusions. The average ratio of tau isoforms c...

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Publicado en:Neurobiol Aging
Autores principales: Niblock, Michael, Hortobágyi, Tibor, Troakes, Claire, Al-Sarraj, Safa, Spickett, Carl, Jones, Rebecca, Shaw, Christopher E., Gallo, Jean-Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2016
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706155/
https://ncbi.nlm.nih.gov/pubmed/26507309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.09.022
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