Heterogeneous Nuclear Ribonucleoprotein E2 (hnRNP E2) Is a Component of TDP-43 Aggregates Specifically in the A and C Pathological Subtypes of Frontotemporal Lobar Degeneration

TAR DNA-binding protein 43 (TDP-43) is the major component of the ubiquitin-positive protein aggregates seen in the majority of frontotemporal lobar degeneration and amyotrophic lateral sclerosis cases. TDP-43 belongs to the heterogeneous nuclear ribonucleoprotein (hnRNP) family that is involved in...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Kattuah, Wejdan, Rogelj, Boris, King, Andrew, Shaw, Christopher E., Hortobágyi, Tibor, Troakes, Claire
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558155/
https://ncbi.nlm.nih.gov/pubmed/31213972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00551
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