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A Failure to Communicate: MYOSIN RESIDUES INVOLVED IN HYPERTROPHIC CARDIOMYOPATHY AFFECT INTER-DOMAIN INTERACTION

Our molecular modeling studies suggest a charge-dependent interaction between residues Glu-497 in the relay domain and Arg-712 in the converter domain of human β-cardiac myosin. To test the significance of this putative interaction, we generated transgenic Drosophila expressing indirect flight muscl...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kronert, William A., Melkani, Girish C., Melkani, Anju, Bernstein, Sanford I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705933/
https://ncbi.nlm.nih.gov/pubmed/26446785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.681874
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