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Disruption of the Aspergillus fumigatus Gene Encoding Nucleolar Protein CgrA Impairs Thermotolerant Growth and Reduces Virulence
Aspergillus fumigatus CgrA is the ortholog of a yeast nucleolar protein that functions in ribosome synthesis. To determine how CgrA contributes to the virulence of A. fumigatus, a ΔcgrA mutant was constructed by targeted gene disruption, and the mutant was reconstituted to wild type by homologous in...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC470587/ https://ncbi.nlm.nih.gov/pubmed/15271935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.8.4731-4740.2004 |
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