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The p53-p21-DREAM-CDE/CHR pathway regulates G(2)/M cell cycle genes
The tumor suppressor p53 functions predominantly as a transcription factor by activating and downregulating gene expression, leading to cell cycle arrest or apoptosis. p53 was shown to indirectly repress transcription of the CCNB2, KIF23 and PLK4 cell cycle genes through the recently discovered p53-...
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| Опубликовано в: : | Nucleic Acids Res |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4705690/ https://ncbi.nlm.nih.gov/pubmed/26384566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv927 |
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