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Characterization of a cAMP responsive transcription factor, Cmr (Rv1675c), in TB complex mycobacteria reveals overlap with the DosR (DevR) dormancy regulon

Mycobacterium tuberculosis (Mtb) Cmr (Rv1675c) is a CRP/FNR family transcription factor known to be responsive to cAMP levels and during macrophage infections. However, Cmr's DNA binding properties, cellular targets and overall role in tuberculosis (TB) complex bacteria have not been characteri...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Ranganathan, Sridevi, Bai, Guangchun, Lyubetskaya, Anna, Knapp, Gwendowlyn S., Peterson, Matthew W., Gazdik, Michaela, C. Gomes, Antonio L., Galagan, James E., McDonough, Kathleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705688/
https://ncbi.nlm.nih.gov/pubmed/26358810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv889
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