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Identification of large-scale genomic variation in cancer genomes using in silico reference models

Identifying large-scale structural variation in cancer genomes continues to be a challenge to researchers. Current methods rely on genome alignments based on a reference that can be a poor fit to highly variant and complex tumor genomes. To address this challenge we developed a method that uses avai...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Killcoyne, Sarah, del Sol, Antonio
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705683/
https://ncbi.nlm.nih.gov/pubmed/26264669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv828
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