Gbp2 interacts with THO/TREX through a novel type of RRM domain

Metazoan SR and SR-like proteins are important regulatory factors in RNA splicing, export, translation and RNA decay. We determined the NMR structures and nucleic acid interaction modes of Gbp2 and Hrb1, two paralogous budding yeast proteins with similarities to mammalian SR proteins. Gbp2 RRM1 and...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Martínez-Lumbreras, Santiago, Taverniti, Valerio, Zorrilla, Silvia, Séraphin, Bertrand, Pérez-Cañadillas, José Manuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Structural Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705658/
https://ncbi.nlm.nih.gov/pubmed/26602689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1303
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