Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by an irreversible airflow limitation in response to inhalation of noxious stimuli, such as cigarette smoke. However, only 15–20 % smokers manifest COPD, suggesting a role for genetic predisposition. Although genome-wide assoc...

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Detalhes bibliográficos
Publicado no:Hum Genomics
Main Authors: Bruse, Shannon, Moreau, Michael, Bromberg, Yana, Jang, Jun-Ho, Wang, Nan, Ha, Hongseok, Picchi, Maria, Lin, Yong, Langley, Raymond J., Qualls, Clifford, Klensney-Tait, Julia, Zabner, Joseph, Leng, Shuguang, Mao, Jenny, Belinsky, Steven A., Xing, Jinchuan, Nyunoya, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705629/
https://ncbi.nlm.nih.gov/pubmed/26744305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-015-0058-7
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