Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis

Metabolic changes can influence inflammatory responses to bacteria. To examine whether localized manipulation of the mevalonate pathway impacts innate immunity, we exploited a unique mucosal disease model, endometritis, where inflammation is a consequence of innate immunity. IL responses to pathogen...

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Bibliografische gegevens
Gepubliceerd in:J Immunol
Hoofdauteurs: Healey, Gareth D., Collier, Christine, Griffin, Sholeem, Schuberth, Hans-Joachim, Sandra, Olivier, Smith, David G., Mahan, Suman, Dieuzy-Labaye, Isabelle, Sheldon, I. Martin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: AAI 2016
Onderwerpen:
Innate Immunity and Inflammation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705593/
https://ncbi.nlm.nih.gov/pubmed/26673142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501080
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