Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis

Metabolic changes can influence inflammatory responses to bacteria. To examine whether localized manipulation of the mevalonate pathway impacts innate immunity, we exploited a unique mucosal disease model, endometritis, where inflammation is a consequence of innate immunity. IL responses to pathogen...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Healey, Gareth D., Collier, Christine, Griffin, Sholeem, Schuberth, Hans-Joachim, Sandra, Olivier, Smith, David G., Mahan, Suman, Dieuzy-Labaye, Isabelle, Sheldon, I. Martin
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2016
Assuntos:
Innate Immunity and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705593/
https://ncbi.nlm.nih.gov/pubmed/26673142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501080
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