Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis

Metabolic changes can influence inflammatory responses to bacteria. To examine whether localized manipulation of the mevalonate pathway impacts innate immunity, we exploited a unique mucosal disease model, endometritis, where inflammation is a consequence of innate immunity. IL responses to pathogen...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Healey, Gareth D., Collier, Christine, Griffin, Sholeem, Schuberth, Hans-Joachim, Sandra, Olivier, Smith, David G., Mahan, Suman, Dieuzy-Labaye, Isabelle, Sheldon, I. Martin
Format: Artigo
Sprog:Inglês
Udgivet: AAI 2016
Fag:
Innate Immunity and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705593/
https://ncbi.nlm.nih.gov/pubmed/26673142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501080
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