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Evidence for genetic regulation of mRNA expression of the dosage-sensitive gene retinoic acid induced-1 (RAI1) in human brain

RAI1 (retinoic acid induced-1) is a dosage-sensitive gene that causes Smith-Magenis syndrome (SMS) when mutated or deleted and Potocki-Lupski Syndrome (PTLS) when duplicated, with psychiatric features commonly observed in both syndromes. How common genetic variants regulate this gene, however, is un...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Li, Tao, Yu, Song, Fan, Yuan, Xi, Wang, Jian, Saffen, David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705554/
https://ncbi.nlm.nih.gov/pubmed/26743651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19010
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