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Thermodynamics and kinetics of amphotericin B self-association in aqueous solution characterized in molecular detail
Amphotericin B (AmB) is a potent but toxic drug commonly used to treat systemic mycoses. Its efficiency as a therapeutic agent depends on its ability to discriminate between mammalian and fungal cell membranes. The association of AmB monomers in an aqueous environment plays an important role in drug...
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| Опубликовано в: : | Sci Rep |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4705489/ https://ncbi.nlm.nih.gov/pubmed/26742886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19109 |
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