Differential effects of the APOE e4 allele on different domains of cognitive ability across the life-course

The association between APOE genotype and cognitive function suggests a positive role for the e2 allele and a negative role for the e4 allele. Both alleles have relatively low frequencies in the general population; hence, meta-analyses have been based on many small, heterogeneous studies. Here, we r...

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Veröffentlicht in:Eur J Hum Genet
Hauptverfasser: Marioni, Riccardo E, Campbell, Archie, Scotland, Generation, Hayward, Caroline, Porteous, David J, Deary, Ian J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705436/
https://ncbi.nlm.nih.gov/pubmed/26395552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.210
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