β-Arrestin 2 Promotes Hepatocyte Apoptosis by Inhibiting Akt Protein

Recent studies reveal that multifunctional protein β-arrestin 2 (Arrb2) modulates cell apoptosis. Survival and various aspects of liver injury were investigated in WT and Arrb2 KO mice after bile duct ligation (BDL). We found that deficiency of Arrb2 enhances survival and attenuates hepatic injury a...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yin, Deling, Yang, Xiaohua, Li, Hui, Fan, Huimin, Zhang, Xiaoli, Feng, Yimin, Stuart, Charles, Hu, Dan, Caudle, Yi, Xie, Nanchang, Liu, Zhongmin, LeSage, Gene
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705381/
https://ncbi.nlm.nih.gov/pubmed/26582201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.655829
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