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β-Arrestin 2 Promotes Hepatocyte Apoptosis by Inhibiting Akt Protein
Recent studies reveal that multifunctional protein β-arrestin 2 (Arrb2) modulates cell apoptosis. Survival and various aspects of liver injury were investigated in WT and Arrb2 KO mice after bile duct ligation (BDL). We found that deficiency of Arrb2 enhances survival and attenuates hepatic injury a...
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| Izdano u: | J Biol Chem |
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| Glavni autori: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4705381/ https://ncbi.nlm.nih.gov/pubmed/26582201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.655829 |
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