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GSK-3 Beta Does Not Stabilize Cryptochrome in the Circadian Clock of Drosophila
Cryptochrome (CRY) is the primary photoreceptor of Drosophila’s circadian clock. It resets the circadian clock by promoting light-induced degradation of the clock protein Timeless (TIM) in the proteasome. Under constant light, the clock stops because TIM is absent, and the flies become arrhythmic. I...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4704813/ https://ncbi.nlm.nih.gov/pubmed/26741981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146571 |
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