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Comparing Residue Clusters from Thermophilic and Mesophilic Enzymes Reveals Adaptive Mechanisms

Understanding how proteins adapt to function at high temperatures is important for deciphering the energetics that dictate protein stability and folding. While multiple principles important for thermostability have been identified, we lack a unified understanding of how internal protein structural a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sammond, Deanne W., Kastelowitz, Noah, Himmel, Michael E., Yin, Hang, Crowley, Michael F., Bomble, Yannick J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704809/
https://ncbi.nlm.nih.gov/pubmed/26741367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145848
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