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The Sphingosine-1-Phosphate Lyase (LegS2) Contributes to the Restriction of Legionella pneumophila in Murine Macrophages

L. pneumophila is the causative agent of Legionnaires’ disease, a human illness characterized by severe pneumonia. In contrast to those derived from humans, macrophages derived from most mouse strains restrict L. pneumophila replication. The restriction of L. pneumophila replication has been shown t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Abu Khweek, Arwa, Kanneganti, Apurva, C. Guttridge D, Denis, Amer, Amal O.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704736/
https://ncbi.nlm.nih.gov/pubmed/26741365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146410
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