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Mapping Quantitative Trait Loci Underlying Function-Valued Traits Using Functional Principal Component Analysis and Multi-Trait Mapping

We previously proposed a simple regression-based method to map quantitative trait loci underlying function-valued phenotypes. In order to better handle the case of noisy phenotype measurements and accommodate the correlation structure among time points, we propose an alternative approach that mainta...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Kwak, Il-Youp, Moore, Candace R., Spalding, Edgar P., Broman, Karl W.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704727/
https://ncbi.nlm.nih.gov/pubmed/26530421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.024133
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