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CYP2D6 copy number distribution in the US population

The cytochrome P450 2D6 (CYP2D6) gene is perhaps the most well characterized gene involved in drug metabolism and is known to have both gene duplication and deletion variants that are inheritable and stable. In a set of over 30 000 deidentified clinical samples we found that 12.6% of all patients te...

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Detalhes bibliográficos
Publicado no:Pharmacogenet Genomics
Main Authors: Beoris, Michelle, Amos Wilson, Jean, Garces, Jorge A., Lukowiak, Andrew A.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704658/
https://ncbi.nlm.nih.gov/pubmed/26551314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000188
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