Intrinsic muscle clock is necessary for musculoskeletal health

The endogenous molecular clock in skeletal muscle is necessary for maintenance of phenotype and function. Loss of Bmal1 solely from adult skeletal muscle (iMSBmal1 (−/−)) results in reductions in specific tension, increased oxidative fibre type and increased muscle fibrosis with no change in feeding...

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Bibliografiska uppgifter
I publikationen:J Physiol
Huvudupphovsmän: Schroder, Elizabeth A., Harfmann, Brianna D., Zhang, Xiping, Srikuea, Ratchakrit, England, Jonathan H., Hodge, Brian A., Wen, Yuan, Riley, Lance A., Yu, Qi, Christie, Alexander, Smith, Jeffrey D., Seward, Tanya, Wolf Horrell, Erin M., Mula, Jyothi, Peterson, Charlotte A., Butterfield, Timothy A., Esser, Karyn A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2015
Ämnen:
Muscle
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704520/
https://ncbi.nlm.nih.gov/pubmed/26486627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271436
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