Intrinsic muscle clock is necessary for musculoskeletal health

The endogenous molecular clock in skeletal muscle is necessary for maintenance of phenotype and function. Loss of Bmal1 solely from adult skeletal muscle (iMSBmal1 (−/−)) results in reductions in specific tension, increased oxidative fibre type and increased muscle fibrosis with no change in feeding...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Schroder, Elizabeth A., Harfmann, Brianna D., Zhang, Xiping, Srikuea, Ratchakrit, England, Jonathan H., Hodge, Brian A., Wen, Yuan, Riley, Lance A., Yu, Qi, Christie, Alexander, Smith, Jeffrey D., Seward, Tanya, Wolf Horrell, Erin M., Mula, Jyothi, Peterson, Charlotte A., Butterfield, Timothy A., Esser, Karyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Muscle
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704520/
https://ncbi.nlm.nih.gov/pubmed/26486627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271436
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