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Essential role of carbonic anhydrase XII in secretory gland fluid and HCO(3) (−) secretion revealed by disease causing human mutation
Fluid and HCO(3) (−) secretion is essential for all epithelia; aberrant secretion is associated with several diseases. . Carbonic anhydrase XII (CA12) is the key carbonic anhydrase in epithelial fluid and HCO(3) (−) secretion and works by activating the ductal Cl(−)–HCO(3) (−) exchanger AE2. Deliver...
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| Veröffentlicht in: | J Physiol |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4704518/ https://ncbi.nlm.nih.gov/pubmed/26486891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271378 |
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