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Molecular pathogenesis of sporadic colorectal cancers

Colorectal cancer (CRC) results from the progressive accumulation of genetic and epigenetic alterations that lead to the transformation of normal colonic mucosa to adenocarcinoma. Approximately 75% of CRCs are sporadic and occur in people without genetic predisposition or family history of CRC. Duri...

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Detalhes bibliográficos
Publicado no:Chin J Cancer
Main Authors: Yamagishi, Hidetsugu, Kuroda, Hajime, Imai, Yasuo, Hiraishi, Hideyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704376/
https://ncbi.nlm.nih.gov/pubmed/26738600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-015-0066-y
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