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Molecular pathogenesis of sporadic colorectal cancers

Colorectal cancer (CRC) results from the progressive accumulation of genetic and epigenetic alterations that lead to the transformation of normal colonic mucosa to adenocarcinoma. Approximately 75% of CRCs are sporadic and occur in people without genetic predisposition or family history of CRC. Duri...

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Bibliografiske detaljer
Udgivet i:Chin J Cancer
Main Authors: Yamagishi, Hidetsugu, Kuroda, Hajime, Imai, Yasuo, Hiraishi, Hideyuki
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704376/
https://ncbi.nlm.nih.gov/pubmed/26738600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-015-0066-y
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