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Developmental Insights into Breast Cancer Intratumoral Heterogeneity

Breast cancer is no longer considered a single disease, but instead is made up of multiple subtypes with genetically and most likely epigenetically heterogeneous tumors composed of numerous clones. Both the hierarchical cancer stem cell and clonal evolution models have been invoked to help explain t...

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Publicado en:Trends Cancer
Autores principales: Zhang, Mei, Rosen, Jeffrey M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704125/
https://ncbi.nlm.nih.gov/pubmed/26753176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2015.10.005
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