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T7 replisome directly overcomes DNA damage

Cells and viruses possess several known ‘restart' pathways to overcome lesions during DNA replication. However, these ‘bypass' pathways leave a gap in replicated DNA or require recruitment of accessory proteins, resulting in significant delays to fork movement or even cell division arrest....

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sun, Bo, Pandey, Manjula, Inman, James T., Yang, Yi, Kashlev, Mikhail, Patel, Smita S., Wang, Michelle D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703881/
https://ncbi.nlm.nih.gov/pubmed/26675048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10260
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