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The propagation of perturbations in rewired bacterial gene networks
What happens to gene expression when you add new links to a gene regulatory network? To answer this question, we profile 85 network rewirings in E. coli. Here we report that concerted patterns of differential expression propagate from reconnected hub genes. The rewirings link promoter regions to dif...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4703840/ https://ncbi.nlm.nih.gov/pubmed/26670742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10105 |
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