Skeletal muscle salt inducible kinase 1 promotes insulin resistance in obesity

OBJECTIVE: Insulin resistance causes type 2 diabetes mellitus and hyperglycemia due to excessive hepatic glucose production and inadequate peripheral glucose uptake. Our objectives were to test the hypothesis that the proposed CREB/CRTC2 inhibitor salt inducible kinase 1 (SIK1) contributes to whole...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Nixon, Mark, Stewart-Fitzgibbon, Randi, Fu, Jingqi, Akhmedov, Dmitry, Rajendran, Kavitha, Mendoza-Rodriguez, Maria G., Rivera-Molina, Yisel A., Gibson, Micah, Berglund, Eric D., Justice, Nicholas J., Berdeaux, Rebecca
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703802/
https://ncbi.nlm.nih.gov/pubmed/26844205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.10.004
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