Genetically Low Antioxidant Protection and Risk of Cardiovascular Disease and Heart Failure in Diabetic Subjects

BACKGROUND: Hyperglycemia-induced oxidative stress is one mechanism believed to underlie diabetic vascular disease. We tested the hypothesis that diabetic subjects heterozygous for extracellular superoxide dismutase (SOD3) R213G, which entails lower antioxidant capacity in tissues, have increased ri...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Kobylecki, Camilla J., Afzal, Shoaib, Nordestgaard, Børge G.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703764/
https://ncbi.nlm.nih.gov/pubmed/26844281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.11.026
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