Genetically Low Antioxidant Protection and Risk of Cardiovascular Disease and Heart Failure in Diabetic Subjects

BACKGROUND: Hyperglycemia-induced oxidative stress is one mechanism believed to underlie diabetic vascular disease. We tested the hypothesis that diabetic subjects heterozygous for extracellular superoxide dismutase (SOD3) R213G, which entails lower antioxidant capacity in tissues, have increased ri...

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Pubblicato in:EBioMedicine
Autori principali: Kobylecki, Camilla J., Afzal, Shoaib, Nordestgaard, Børge G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703764/
https://ncbi.nlm.nih.gov/pubmed/26844281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.11.026
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