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Prospective Testing and Redesign of a Temporal Biomarker Based Risk Model for Patients With Septic Shock: Implications for Septic Shock Biology

The temporal version of the pediatric sepsis biomarker risk model (tPERSEVERE) estimates the risk of a complicated course in children with septic shock based on biomarker changes from days 1 to 3 of septic shock. We validated tPERSEVERE performance in a prospective cohort, with an a priori plan to r...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Wong, Hector R., Cvijanovich, Natalie Z., Anas, Nick, Allen, Geoffrey L., Thomas, Neal J., Bigham, Michael T., Weiss, Scott L., Fitzgerald, Julie, Checchia, Paul A., Meyer, Keith, Quasney, Michael, Hall, Mark, Gedeit, Rainer, Freishtat, Robert J., Nowak, Jeffrey, Raj, Shekhar S., Gertz, Shira, Howard, Kelli, Harmon, Kelli, Lahni, Patrick, Frank, Erin, Hart, Kimberly W., Lindsell, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703723/
https://ncbi.nlm.nih.gov/pubmed/26844289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.11.035
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