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Recognition of distinct RNA motifs by the clustered CCCH zinc fingers of neuronal protein Unkempt

Unkempt is an evolutionarily conserved RNA-binding protein that regulates translation of its target genes and is required for the establishment of the early bipolar neuronal morphology. Here we determined the X-ray crystal structure of mouse Unkempt and show that its six CCCH zinc fingers (ZnFs) for...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Murn, Jernej, Teplova, Marianna, Zarnack, Kathi, Shi, Yang, Patel, Dinshaw J
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703518/
https://ncbi.nlm.nih.gov/pubmed/26641712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3140
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