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Identification and Functional Characterizations of N-Terminal α-N-Methylation and Phosphorylation of Serine 461 in Human Poly(ADP-ribose) Polymerase 3

Poly(ADP-ribose) polymerase 3 (PARP3) is a member of the PARP family enzymes which catalyze the ADP-ribosylation of proteins. PARP3 plays an important role in DNA damage repair and mitotic progression. In this study, we identified, using mass spectrometric techniques, two novel post-translational mo...

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Bibliographic Details
Published in:J Proteome Res
Main Authors: Dai, Xiaoxia, Rulten, Stuart L., You, Changjun, Caldecott, Keith W., Wang, Yinsheng
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703312/
https://ncbi.nlm.nih.gov/pubmed/25886813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.5b00126
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