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Essential role of D1R in the regulation of mTOR complex1 signaling induced by cocaine

The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that is involved in neuronal adaptions that underlie cocaine-induced sensitization and reward. mTOR exists in two functionally distinct multi-component complexes known as mTORC1 and mTORC2. In this study, we show that increased mT...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Sutton, Laurie P., Caron, Marc G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703076/
https://ncbi.nlm.nih.gov/pubmed/26314207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.08.024
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