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Target selection by natural and redesigned PUF proteins

Pumilio/fem-3 mRNA binding factor (PUF) proteins bind RNA with sequence specificity and modularity, and have become exemplary scaffolds in the reengineering of new RNA specificities. Here, we report the in vivo RNA binding sites of wild-type (WT) and reengineered forms of the PUF protein Saccharomyc...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Porter, Douglas F., Koh, Yvonne Y., VanVeller, Brett, Raines, Ronald T., Wickens, Marvin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703012/
https://ncbi.nlm.nih.gov/pubmed/26668354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508501112
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