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Casein kinase II promotes target silencing by miRISC through direct phosphorylation of the DEAD-box RNA helicase CGH-1

MicroRNAs (miRNAs) play essential, conserved roles in diverse developmental processes through association with the miRNA-induced silencing complex (miRISC). Whereas fundamental insights into the mechanistic framework of miRNA biogenesis and target gene silencing have been established, posttranslatio...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Alessi, Amelia F., Khivansara, Vishal, Han, Ting, Freeberg, Mallory A., Moresco, James J., Tu, Patricia G., Montoye, Eric, Yates, John R., Karp, Xantha, Kim, John K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702986/
https://ncbi.nlm.nih.gov/pubmed/26669440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509499112
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